Tweet

Share

Share

It can be challenging to develop a neural network predictive model for a new dataset.

One approach is to first inspect the dataset and develop ideas for what models might work, then explore the learning dynamics of simple models on the dataset, then finally develop and tune a model for the dataset with a robust test harness.

This process can be used to develop effective neural network models for classification and regression predictive modeling problems.

In this tutorial, you will discover how to develop a Multilayer Perceptron neural network model for the cancer survival binary classification dataset.

After completing this tutorial, you will know:

How to load and summarize the cancer survival dataset and use the results to suggest data preparations and model configurations to use.

How to explore the learning dynamics of simple MLP models on the dataset.

How to develop robust estimates of model performance, tune model performance and make predictions on new data.

Let’s get started.

Develop a Neural Network for Cancer Survival DatasetPhoto by Bernd Thaller, some rights reserved.

Tutorial Overview

This tutorial is divided into 4 parts; they are:

Haberman Breast Cancer Survival Dataset

Neural Network Learning Dynamics

Robust Model Evaluation

Final Model and Make Predictions

Haberman Breast Cancer Survival Dataset

The first step is to define and explore the dataset.

We will be working with the “haberman” standard binary classification dataset.

The dataset describes breast cancer patient data and the outcome is patient survival. Specifically whether the patient survived for five years or longer, or whether the patient did not survive.

This is a standard dataset used in the study of imbalanced classification. According to the dataset description, the operations were conducted between 1958 and 1970 at the University of Chicago’s Billings Hospital.

There are 306 examples in the dataset, and there are 3 input variables; they are:

The age of the patient at the time of the operation.

The two-digit year of the operation.

The number of “positive axillary nodes” detected, a measure of whether cancer has spread.

As such, we have no control over the selection of cases that make up the dataset or features to use in those cases, other than what is available in the dataset.

Although the dataset describes breast cancer patient survival, given the small dataset size and the fact the data is based on breast cancer diagnosis and operations many decades ago, any models built on this dataset are not expected to generalize.

Note: to be crystal clear, we are NOT “solving breast cancer“. We are exploring a standard classification dataset.

Below is a sample of the first 5 rows of the dataset30,64,1,1

30,62,3,1

30,65,0,1

31,59,2,1

31,65,4,1

…You can learn more about the dataset here:

Haberman Survival Dataset (haberman.csv)

Haberman Survival Dataset Details (haberman.names)

We can load the dataset as a pandas DataFrame directly from the URL; for example:# load the haberman dataset and summarize the shape

from pandas import read_csv

# define the location of the dataset

url = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

# load the dataset

df = read_csv(url, header=None)

# summarize shape

print(df.shape)Running the example loads the dataset directly from the URL and reports the shape of the dataset.

In this case, we can confirm that the dataset has 4 variables (3 input and one output) and that the dataset has 306 rows of data.

This is not many rows of data for a neural network and suggests that a small network, perhaps with regularization, would be appropriate.

It also suggests that using k-fold cross-validation would be a good idea given that it will give a more reliable estimate of model performance than a train/test split and because a single model will fit in seconds instead of hours or days with the largest datasets.(306, 4)Next, we can learn more about the dataset by looking at summary statistics and a plot of the data.# show summary statistics and plots of the haberman dataset

from pandas import read_csv

from matplotlib import pyplot

# define the location of the dataset

url = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

# load the dataset

df = read_csv(url, header=None)

# show summary statistics

print(df.describe())

# plot histograms

df.hist()

pyplot.show()Running the example first loads the data before and then prints summary statistics for each variable.

We can see that values vary with different means and standard deviations, perhaps some normalization or standardization would be required prior to modeling.0 1 2 3

count 306.000000 306.000000 306.000000 306.000000

mean 52.457516 62.852941 4.026144 1.264706

std 10.803452 3.249405 7.189654 0.441899

min 30.000000 58.000000 0.000000 1.000000

25% 44.000000 60.000000 0.000000 1.000000

50% 52.000000 63.000000 1.000000 1.000000

75% 60.750000 65.750000 4.000000 2.000000

max 83.000000 69.000000 52.000000 2.000000A histogram plot is then created for each variable.

We can see that perhaps the first variable has a Gaussian-like distribution and the next two input variables may have an exponential distribution.

We may have some benefit in using a power transform on each variable in order to make the probability distribution less skewed which will likely improve model performance.

Histograms of the Haberman Breast Cancer Survival Classification Dataset

We can see some skew in the distribution of examples between the two classes, meaning that the classification problem is not balanced. It is imbalanced.

It may be helpful to know how imbalanced the dataset actually is.

We can use the Counter object to count the number of examples in each class, then use those counts to summarize the distribution.

The complete example is listed below.# summarize the class ratio of the haberman dataset

from pandas import read_csv

from collections import Counter

# define the location of the dataset

url = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

# define the dataset column names

columns = [‘age’, ‘year’, ‘nodes’, ‘class’]

# load the csv file as a data frame

dataframe = read_csv(url, header=None, names=columns)

# summarize the class distribution

target = dataframe[‘class’].values

counter = Counter(target)

for k,v in counter.items():

per = v / len(target) * 100

print(‘Class=%d, Count=%d, Percentage=%.3f%%’ % (k, v, per))Running the example summarizes the class distribution for the dataset.

We can see that class 1 for survival has the most examples at 225, or about 74 percent of the dataset. We can see class 2 for non-survival has fewer examples at 81, or about 26 percent of the dataset.

The class distribution is skewed, but it is not severely imbalanced.Class=1, Count=225, Percentage=73.529%

Class=2, Count=81, Percentage=26.471%This is helpful because if we use classification accuracy, then any model that achieves an accuracy less than about 73.5% does not have skill on this dataset.

Now that we are familiar with the dataset, let’s explore how we might develop a neural network model.

Neural Network Learning Dynamics

We will develop a Multilayer Perceptron (MLP) model for the dataset using TensorFlow.

We cannot know what model architecture of learning hyperparameters would be good or best for this dataset, so we must experiment and discover what works well.

Given that the dataset is small, a small batch size is probably a good idea, e.g. 16 or 32 rows. Using the Adam version of stochastic gradient descent is a good idea when getting started as it will automatically adapt the learning rate and works well on most datasets.

Before we evaluate models in earnest, it is a good idea to review the learning dynamics and tune the model architecture and learning configuration until we have stable learning dynamics, then look at getting the most out of the model.

We can do this by using a simple train/test split of the data and review plots of the learning curves. This will help us see if we are over-learning or under-learning; then we can adapt the configuration accordingly.

First, we must ensure all input variables are floating-point values and encode the target label as integer values 0 and 1….

# ensure all data are floating point values

X = X.astype(‘float32′)

# encode strings to integer

y = LabelEncoder().fit_transform(y)Next, we can split the dataset into input and output variables, then into 67/33 train and test sets.

We must ensure that the split is stratified by the class ensuring that the train and test sets have the same distribution of class labels as the main dataset….

# split into input and output columns

X, y = df.values[:, :-1], df.values[:, -1]

# split into train and test datasets

X_train, X_test, y_train, y_test = train_test_split(X, y, test_size=0.5, stratify=y, random_state=3)We can define a minimal MLP model. In this case, we will use one hidden layer with 10 nodes and one output layer (chosen arbitrarily). We will use the ReLU activation function in the hidden layer and the “he_normal” weight initialization, as together, they are a good practice.

The output of the model is a sigmoid activation for binary classification and we will minimize binary cross-entropy loss….

# determine the number of input features

n_features = X.shape[1]

# define model

model = Sequential()

model.add(Dense(10, activation=’relu’, kernel_initializer=’he_normal’, input_shape=(n_features,)))

model.add(Dense(1, activation=’sigmoid’))

# compile the model

model.compile(optimizer=’adam’, loss=’binary_crossentropy’)We will fit the model for 200 training epochs (chosen arbitrarily) with a batch size of 16 because it is a small dataset.

We are fitting the model on raw data, which we think might be a good idea, but it is an important starting point….

# fit the model

history = model.fit(X_train, y_train, epochs=200, batch_size=16, verbose=0, validation_data=(X_test,y_test))At the end of training, we will evaluate the model’s performance on the test dataset and report performance as the classification accuracy….

# predict test set

yhat = model.predict_classes(X_test)

# evaluate predictions

score = accuracy_score(y_test, yhat)

print(‘Accuracy: %.3f’ % score)Finally, we will plot learning curves of the cross-entropy loss on the train and test sets during training….

# plot learning curves

pyplot.title(‘Learning Curves’)

pyplot.xlabel(‘Epoch’)

pyplot.ylabel(‘Cross Entropy’)

pyplot.plot(history.history[‘loss’], label=’train’)

pyplot.plot(history.history[‘val_loss’], label=’val’)

pyplot.legend()

pyplot.show()Tying this all together, the complete example of evaluating our first MLP on the cancer survival dataset is listed below.# fit a simple mlp model on the haberman and review learning curves

from pandas import read_csv

from sklearn.model_selection import train_test_split

from sklearn.preprocessing import LabelEncoder

from sklearn.metrics import accuracy_score

from tensorflow.keras import Sequential

from tensorflow.keras.layers import Dense

from matplotlib import pyplot

# load the dataset

path = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

df = read_csv(path, header=None)

# split into input and output columns

X, y = df.values[:, :-1], df.values[:, -1]

# ensure all data are floating point values

X = X.astype(‘float32′)

# encode strings to integer

y = LabelEncoder().fit_transform(y)

# split into train and test datasets

X_train, X_test, y_train, y_test = train_test_split(X, y, test_size=0.5, stratify=y, random_state=3)

# determine the number of input features

n_features = X.shape[1]

# define model

model = Sequential()

model.add(Dense(10, activation=’relu’, kernel_initializer=’he_normal’, input_shape=(n_features,)))

model.add(Dense(1, activation=’sigmoid’))

# compile the model

model.compile(optimizer=’adam’, loss=’binary_crossentropy’)

# fit the model

history = model.fit(X_train, y_train, epochs=200, batch_size=16, verbose=0, validation_data=(X_test,y_test))

# predict test set

yhat = model.predict_classes(X_test)

# evaluate predictions

score = accuracy_score(y_test, yhat)

print(‘Accuracy: %.3f’ % score)

# plot learning curves

pyplot.title(‘Learning Curves’)

pyplot.xlabel(‘Epoch’)

pyplot.ylabel(‘Cross Entropy’)

pyplot.plot(history.history[‘loss’], label=’train’)

pyplot.plot(history.history[‘val_loss’], label=’val’)

pyplot.legend()

pyplot.show()Running the example first fits the model on the training dataset, then reports the classification accuracy on the test dataset.

Kick-start your project with my new book Data Preparation for Machine Learning, including step-by-step tutorials and the Python source code files for all examples.

In this case we can see that the model performs better than a no-skill model, given that the accuracy is above about 73.5%.Accuracy: 0.765Line plots of the loss on the train and test sets are then created.

We can see that the model quickly finds a good fit on the dataset and does not appear to be over or underfitting.

Learning Curves of Simple Multilayer Perceptron on Cancer Survival Dataset

Now that we have some idea of the learning dynamics for a simple MLP model on the dataset, we can look at developing a more robust evaluation of model performance on the dataset.

Robust Model Evaluation

The k-fold cross-validation procedure can provide a more reliable estimate of MLP performance, although it can be very slow.

This is because k models must be fit and evaluated. This is not a problem when the dataset size is small, such as the cancer survival dataset.

We can use the StratifiedKFold class and enumerate each fold manually, fit the model, evaluate it, and then report the mean of the evaluation scores at the end of the procedure….

# prepare cross validation

kfold = KFold(10)

# enumerate splits

scores = list()

for train_ix, test_ix in kfold.split(X, y):

# fit and evaluate the model…

…

…

# summarize all scores

print(‘Mean Accuracy: %.3f (%.3f)’ % (mean(scores), std(scores)))We can use this framework to develop a reliable estimate of MLP model performance with our base configuration, and even with a range of different data preparations, model architectures, and learning configurations.

It is important that we first developed an understanding of the learning dynamics of the model on the dataset in the previous section before using k-fold cross-validation to estimate the performance. If we started to tune the model directly, we might get good results, but if not, we might have no idea of why, e.g. that the model was over or under fitting.

If we make large changes to the model again, it is a good idea to go back and confirm that the model is converging appropriately.

The complete example of this framework to evaluate the base MLP model from the previous section is listed below.# k-fold cross-validation of base model for the haberman dataset

from numpy import mean

from numpy import std

from pandas import read_csv

from sklearn.model_selection import StratifiedKFold

from sklearn.preprocessing import LabelEncoder

from sklearn.metrics import accuracy_score

from tensorflow.keras import Sequential

from tensorflow.keras.layers import Dense

from matplotlib import pyplot

# load the dataset

path = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

df = read_csv(path, header=None)

# split into input and output columns

X, y = df.values[:, :-1], df.values[:, -1]

# ensure all data are floating point values

X = X.astype(‘float32′)

# encode strings to integer

y = LabelEncoder().fit_transform(y)

# prepare cross validation

kfold = StratifiedKFold(10, random_state=1)

# enumerate splits

scores = list()

for train_ix, test_ix in kfold.split(X, y):

# split data

X_train, X_test, y_train, y_test = X[train_ix], X[test_ix], y[train_ix], y[test_ix]

# determine the number of input features

n_features = X.shape[1]

# define model

model = Sequential()

model.add(Dense(10, activation=’relu’, kernel_initializer=’he_normal’, input_shape=(n_features,)))

model.add(Dense(1, activation=’sigmoid’))

# compile the model

model.compile(optimizer=’adam’, loss=’binary_crossentropy’)

# fit the model

model.fit(X_train, y_train, epochs=200, batch_size=16, verbose=0)

# predict test set

yhat = model.predict_classes(X_test)

# evaluate predictions

score = accuracy_score(y_test, yhat)

print(‘>%.3f’ % score)

scores.append(score)

# summarize all scores

print(‘Mean Accuracy: %.3f (%.3f)’ % (mean(scores), std(scores)))Running the example reports the model performance each iteration of the evaluation procedure and reports the mean and standard deviation of classification accuracy at the end of the run.

Kick-start your project with my new book Data Preparation for Machine Learning, including step-by-step tutorials and the Python source code files for all examples.

In this case, we can see that the MLP model achieved a mean accuracy of about 75.2 percent, which is pretty close to our rough estimate in the previous section.

This confirms our expectation that the base model configuration may work better than a naive model for this dataset>0.742

>0.774

>0.774

>0.806

>0.742

>0.710

>0.767

>0.800

>0.767

>0.633

Mean Accuracy: 0.752 (0.048)Is this a good result?

In fact, this is a challenging classification problem and achieving a score above about 74.5% is good.

Next, let’s look at how we might fit a final model and use it to make predictions.

Final Model and Make Predictions

Once we choose a model configuration, we can train a final model on all available data and use it to make predictions on new data.

In this case, we will use the model with dropout and a small batch size as our final model.

We can prepare the data and fit the model as before, although on the entire dataset instead of a training subset of the dataset….

# split into input and output columns

X, y = df.values[:, :-1], df.values[:, -1]

# ensure all data are floating point values

X = X.astype(‘float32′)

# encode strings to integer

le = LabelEncoder()

y = le.fit_transform(y)

# determine the number of input features

n_features = X.shape[1]

# define model

model = Sequential()

model.add(Dense(10, activation=’relu’, kernel_initializer=’he_normal’, input_shape=(n_features,)))

model.add(Dense(1, activation=’sigmoid’))

# compile the model

model.compile(optimizer=’adam’, loss=’binary_crossentropy’)We can then use this model to make predictions on new data.

First, we can define a row of new data….

# define a row of new data

row = [30,64,1]Note: I took this row from the first row of the dataset and the expected label is a ‘1’.

We can then make a prediction….

# make prediction

yhat = model.predict_classes([row])Then invert the transform on the prediction, so we can use or interpret the result in the correct label (which is just an integer for this dataset)….

# invert transform to get label for class

yhat = le.inverse_transform(yhat)And in this case, we will simply report the prediction….

# report prediction

print(‘Predicted: %s’ % (yhat[0]))Tying this all together, the complete example of fitting a final model for the haberman dataset and using it to make a prediction on new data is listed below.# fit a final model and make predictions on new data for the haberman dataset

from pandas import read_csv

from sklearn.preprocessing import LabelEncoder

from sklearn.metrics import accuracy_score

from tensorflow.keras import Sequential

from tensorflow.keras.layers import Dense

from tensorflow.keras.layers import Dropout

# load the dataset

path = ‘https://raw.githubusercontent.com/jbrownlee/Datasets/master/haberman.csv’

df = read_csv(path, header=None)

# split into input and output columns

X, y = df.values[:, :-1], df.values[:, -1]

# ensure all data are floating point values

X = X.astype(‘float32′)

# encode strings to integer

le = LabelEncoder()

y = le.fit_transform(y)

# determine the number of input features

n_features = X.shape[1]

# define model

model = Sequential()

model.add(Dense(10, activation=’relu’, kernel_initializer=’he_normal’, input_shape=(n_features,)))

model.add(Dense(1, activation=’sigmoid’))

# compile the model

model.compile(optimizer=’adam’, loss=’binary_crossentropy’)

# fit the model

model.fit(X, y, epochs=200, batch_size=16, verbose=0)

# define a row of new data

row = [30,64,1]

# make prediction

yhat = model.predict_classes([row])

# invert transform to get label for class

yhat = le.inverse_transform(yhat)

# report prediction

print(‘Predicted: %s’ % (yhat[0]))Running the example fits the model on the entire dataset and makes a prediction for a single row of new data.

Kick-start your project with my new book Data Preparation for Machine Learning, including step-by-step tutorials and the Python source code files for all examples.

In this case, we can see that the model predicted a “1” label for the input row.Predicted: 1

Further Reading

This section provides more resources on the topic if you are looking to go deeper.

Tutorials

How to Develop a Probabilistic Model of Breast Cancer Patient Survival

How to Develop a Neural Net for Predicting Disturbances in the Ionosphere

Best Results for Standard Machine Learning Datasets

TensorFlow 2 Tutorial: Get Started in Deep Learning With tf.keras

A Gentle Introduction to k-fold Cross-Validation

Summary

In this tutorial, you discovered how to develop a Multilayer Perceptron neural network model for the cancer survival binary classification dataset.

Specifically, you learned:

How to load and summarize the cancer survival dataset and use the results to suggest data preparations and model configurations to use.

How to explore the learning dynamics of simple MLP models on the dataset.

How to develop robust estimates of model performance, tune model performance and make predictions on new data.

Do you have any questions?

Ask your questions in the comments below and I will do my best to answer.

Tweet

Share

Share

The post Develop a Neural Network for Cancer Survival Dataset appeared first on Machine Learning Mastery.